Semaglutide Microdose (Injections)
- Product overview
- Why Glp-1s
- How it works
- Treatment process
- Explore other treatments
- Why REG3N
- Common questions
- Treatment information
Compounded Semaglutide with Glycine and B12
From $196/mo*
Can help suppress appetite and slow digestion. Personalized ingredients like Glycine and B12 may support muscle maintenance and nutrient deficiencies during a caloric deficit.
*Billed quarterly with a three-month commitment paid up front.
WHY GLP-1S
Natural hormone breaks down in minutes. GLP-1s last days.
Natural GLP-1 lasts ~2 minutes
Every time you eat, your gut releases a hormone called GLP-1 that signals fullness, triggers insulin release, and slows digestion. An enzyme called DPP-4 destroys it within 1 to 2 minutes.
Source: Nauck & Meier, "Are All GLP-1 Agonists Equal in the Treatment of Type 2 Diabetes?," European Journal of Endocrinology (2019); Gentilella et al., Diabetes/Metabolism Research and Reviews (2019)
Published study facts
Engineered to last longer
GLP-1 receptor agonists are lab-engineered versions of this hormone, modified to resist DPP-4 breakdown and stay active long enough to sustain appetite control and blood sugar regulation.
Source: Nauck & Meier, "Are All GLP-1 Agonists Equal in the Treatment of Type 2 Diabetes?," European Journal of Endocrinology (2019); Gentilella et al., Diabetes/Metabolism Research and Reviews (2019)
Sustained effects: minutes to days
The result: half-lives ranging from 2.5 hours to approximately 7 days — up to 5,000 times longer than the natural hormone.
Source: Nauck & Meier, "Are All GLP-1 Agonists Equal in the Treatment of Type 2 Diabetes?," European Journal of Endocrinology (2019); Gentilella et al., Diabetes/Metabolism Research and Reviews (2019)
Charts and graphics are illustrative representations intended to communicate published research findings and the known pharmacologic properties of a medication class or active ingredient. Visualizations may simplify, normalize, or model study data for educational purposes and should not be interpreted as guarantees of individual clinical outcomes. References to medication classes, mechanisms, or published studies are intended to illustrate general pharmacologic concepts and do not establish that any specific medication, formulation, or treatment program will produce identical results. Compounded medications are not evaluated by the FDA for safety, quality or efficacy.
HOW GLP-1 RA WORKS
Supports feeling fuller for longer.
Semaglutide is a GLP-1 receptor agonist (GLP-1 RA) that mimics the GLP-1 hormone produced in the gut. Receptors are located in the brain, gut, heart, and pancreas, where activation supports appetite regulation, blood sugar balance, and metabolic function.
Activates GLP-1 receptors
GLP-1 is a hormone your gut produces naturally, lasting only 1-2 minutes in the body. GLP-1 receptor agonists are engineered to activate the same receptors for days instead of minutes, providing sustained appetite regulation and metabolic support.
Supports metabolic health
GLP-1 receptor agonists have been shown in studies to lower blood pressure, improve blood sugar regulation, and reduce lipid levels and inflammatory markers. These effects appear independent of weight loss, driven by direct GLP-1 receptor activation in the heart, blood vessels, and kidneys.
Signals satiety
GLP-1 receptors in the brain suppress hunger and amplify fullness signals. The GLP-1 hormone can also slow digestion, extending a feeling of fullness after meals.
Step 1
Medical intake
Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.
A few minutes
Step 2
Doctor review
A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*
Within 72 hours
Step 3
Fast shipping
Approved medications ship directly to your door in discreet packaging.
2-5 business days
Step 4
Unlimited messaging
Your doctor is available via chat any time for additional support. Video consults available. The same prescription framework as REG3N's medical team. *Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.
Up to 12 months
Proactive care
Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.
Transparent pricing
No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.
Board-certified doctors
Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.
Curated by longevity experts
Every protocol is built by medical experts, based on longevity research from REG3N's science team.
What is Personalized Semaglutide?
Semaglutide is used for weight management in overweight or obese adults. Additional ingredients (glycine and vitamin B12) support the body during treatment, potentially helping you hold onto muscle and avoid vitamin deficiencies.
How do you take Personalized Semaglutide?
Personalized semaglutide is available via REG3N in a weekly injectable form.
What are the side effects of Personalized Semaglutide?
Nausea, vomiting, diarrhea, and constipation are most frequently reported. They typically improve within a few weeks as your body adjusts.
Who shouldn’t take Personalized Semaglutide?
Not recommended for people with a personal or family history of medullary thyroid cancer or MEN2. Your doctor will evaluate whether Personalized Semaglutide is appropriate for you.
Disclaimer: This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program.
Can help suppress appetite and slow digestion. Personalized ingredients like Glycine and B12 may support muscle maintenance and nutrient deficiencies during a caloric deficit.