Arousal Peptide (Injections)
- Product overview
- Why Bremelanotide
- How it works
- Treatment process
- Explore other treatments
- Why REG3N
- Common questions
- Treatment information
(bremelanotide)
From $73/mo*
Can increase sexual desire by activating brain pathways involved in desire and arousal.
*Billed quarterly with a three-month commitment paid up front.
WHY BREMELANOTIDE
Desire starts in the brain. Bremelanotide activates the pathway.
RECONNECT Trials (2019)
In two trials of over 1,200 premenopausal women with low sexual desire, bremelanotide increased desire scores by 0.5 points versus 0.2 with placebo (p < 0.001), with benefits appearing within the first few weeks and maintained over 6 months.
Source: Kingsberg et al., "Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials," Obstetrics & Gynecology (2019) — the RECONNECT Trials
RECONNECT Trials (2019)
Bremelanotide also reduced emotional distress about low desire by 0.33 points more than placebo (p < 0.001), with women reporting increased feelings of desire, physical arousal, and improvements in relationship quality.
Source: Kingsberg et al., "Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials," Obstetrics & Gynecology (2019) — the RECONNECT Trials
NEJM (2024)
80% of eligible women opted to continue treatment and maintained improvements in desire and distress through 18 months.
Source: Simon et al., "Long-Term Safety and Efficacy of Bremelanotide for HSDD," Obstetrics & Gynecology (2019) & Davis, "Sexual Dysfunction in Women," NEJM (2024)
Charts and graphics are illustrative representations intended to communicate published research findings and the known pharmacologic properties of a medication class or active ingredient. Visualizations may simplify, normalize, or model study data for educational purposes and should not be interpreted as guarantees of individual clinical outcomes. References to medication classes, mechanisms, or published studies are intended to illustrate general pharmacologic concepts and do not establish that any specific medication, formulation, or treatment program will produce identical results. Compounded medications are not evaluated by the FDA for safety, quality or efficacy.
HOW BREMELANOTIDE WORKS
Activates brain pathways linked to desire.
Bremelanotide activates melanocortin receptors in the brain. These receptors are part of the neural pathway that regulates sexual desire. Unlike treatments that act on blood flow or hormones, bremelanotide works upstream at the source of desire itself.
Activates melanocortin receptors
Bremelanotide activates melanocortin receptors in the brain, particularly the MC4R subtype, which is found in areas of the brain believed to be involved in sexual function.
Increases feelings of sexual desire
In clinical trials, women using bremelanotide reported increased feelings of sexual desire and reduced distress related to low desire.
Engages dopamine pathways
This receptor activation is thought to stimulate the release of dopamine — a brain chemical associated with arousal and motivation
Step 1
Medical intake
Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.
A few minutes
Step 2
Doctor review
A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*
Within 72 hours
Step 3
Fast shipping
Approved medications ship directly to your door in discreet packaging.
2-5 business days
Step 4
Unlimited messaging
Your doctor is available via chat any time for additional support. Video consults available. The same prescription framework as REG3N's medical team. *Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.
Up to 12 months
Proactive care
Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.
Transparent pricing
No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.
Board-certified doctors
Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.
Curated by longevity experts
Every protocol is built by medical experts, based on longevity research from REG3N's science team.
What is Arousal Peptide?
Arousal Peptide contains bremelanotide, an FDA-approved treatment for hypoactive sexual desire disorder in premenopausal women. It can increase sexual desire and reduce distress related to low desire. Providers also prescribe it off-label for men without erectile dysfunction, but who have hypoactive sexual desire.
How do you take Arousal Peptide?
Inject Arousal Peptide (Injections) into the abdomen or thigh approximately 45 to 60 minutes before anticipated sexual activity. For Arousal Peptide (Nasal Spray), spray twice into each nostril 30 minutes before sexual activity. No more than one dose in 24 hours, and no more than eight per month.
What are the side effects of Arousal Peptide?
The most common side effects are nausea, flushing, injection site reactions (for injections), headache, and vomiting. Side effects typically lessen with subsequent use.
Who shouldn’t take Arousal Peptide?
Not recommended for people with uncontrolled high blood pressure or known cardiovascular disease. Your doctor will evaluate whether Arousal Peptide is appropriate for you.
Disclaimer: This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program.
Can increase sexual desire by activating brain pathways involved in desire and arousal.