Jardiance®
- Product overview
- Why Jardiance®
- How it works
- Treatment process
- Explore other treatments
- Why REG3N
- Common questions
- Treatment information
(empagliflozin)
From $1,200/mo*
Blocks the kidney protein that pulls glucose back into your blood, helping excrete sugar.
*Billed quarterly with a three-month commitment paid up front.
WHY JARDIANCE®
Your kidneys reabsorb glucose. Jardiance® reduces that reabsorption.
Can reduce sugar reabsorption
In a study of 30 people — half with type 2 diabetes and half without — Jardiance® reduced the kidneys' maximum sugar-recycling capacity by 44–53% within just 2 days, and by 65–75% after 14 days.
Source: Al-Jobori et al., "Empagliflozin and Kinetics of Renal Glucose Transport in Healthy Individuals and Individuals With Type 2 Diabetes," Diabetes (2017)
Promotes daily sugar excretion
Patients taking Jardiance® excrete approximately 64 grams of sugar per day with the 10 mg dose and 78 grams per day with the 25 mg dose — that's roughly equivalent to 16–20 teaspoons of sugar being removed from the body every day.
Source: Jardiance (empagliflozin) FDA Prescribing Information (2026) & Heise et al., "Pharmacodynamic Effects of Single and Multiple Doses of Empagliflozin," Clinical Therapeutics (2016)
May help protect heart and kidneys
In the landmark EMPA-REG OUTCOME trial, empagliflozin reduced cardiovascular death by 38% and slowed kidney disease progression by 39% in patients with type 2 diabetes and heart disease.
Source: Braunwald, "Gliflozins in the Management of Cardiovascular Disease," New England Journal of Medicine (2022) & Jardiance FDA-Approved Indications (2026)
Charts and graphics are illustrative representations intended to communicate published research findings and the known pharmacologic properties of the referenced medication. Visualizations may simplify, normalize, or model study data for educational purposes and should not be interpreted as guarantees of individual clinical outcomes or expected results.
HOW JARDIANCE® WORKS
Lowers glucose.
Supports metabolic health. Jardiance® inhibits SGLT2 in the kidneys, the transporter that pulls glucose and sodium back into your blood. This helps support cardiovascular health, kidney function, and metabolic health.
Inhibits SGLT2
Jardiance® binds to and inhibits SGLT2, the primary transporter in the kidneys responsible for reabsorbing filtered glucose back into the bloodstream.
Reduces cardiometabolic load
In clinical trials, daily dosing produced reductions in cardiovascular death, heart failure hospitalization, and progression of chronic kidney disease.
Helps excrete glucose and sodium
With SGLT2 inhibited, excess glucose leaves the body through urine. Reduced sodium reabsorption lowers blood volume and intraglomerular pressure without raising heart rate.
Step 1
Medical intake
Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.
A few minutes
Step 2
Doctor review
A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*
Within 72 hours
Step 3
Fast shipping
Approved medications ship directly to your door in discreet packaging.
2-5 business days
Step 4
Unlimited messaging
Your doctor is available via chat any time for additional support. Video consults available. The same prescription framework as REG3N's medical team. *Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.
Up to 12 months
Proactive care
Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.
Transparent pricing
No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.
Board-certified doctors
Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.
Curated by longevity experts
Every protocol is built by medical experts, based on longevity research from REG3N's science team.
What is Jardiance®?
Jardiance® (empagliflozin) is an FDA-approved treatment for type 2 diabetes, heart failure, and chronic kidney disease. Off-label, it's sometimes prescribed by doctors within a longevity medicine framework.
How do you take Jardiance®?
Jardiance® is a daily oral tablet, taken once daily in the morning, with or without food. Always follow dosage instructions from your doctor.
What are the side effects of Jardiance®?
The most frequently reported side effects are urinary tract infections and genital yeast infections, which can occur in both men and women because Jardiance® increases glucose in the urine. Increased urination, mild dehydration, and lower blood pressure are also common. These are typically mild and tend to resolve as your body adjusts, with good hydration, hygiene, and standard treatment. Tell your doctor if side effects persist or feel disruptive.
Who shouldn't take Jardiance®?
Jardiance® is not recommended for people with type 1 diabetes (due to an increased risk of diabetic ketoacidosis), severe kidney impairment (eGFR below 30 mL/min/1.73 m²), or during the second and third trimesters of pregnancy. Extra caution is warranted for people on insulin or sulfonylureas, on diuretics or blood-pressure medications, with a history of recurrent genital or urinary infections, or with prior lower-limb amputations or foot ulcers. Your doctor will review your full medication list and health history before prescribing.
Disclaimer: This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program.
Blocks the kidney protein that pulls glucose back into your blood, helping excrete sugar.