Brenzavvy®
- Product overview
- Why Brenzavvy®
- How it works
- Treatment process
- Explore other treatments
- Why REG3N
- Common questions
- Treatment information
(bexagliflozin)
From $143/mo*
Can help kidneys flush excess glucose, supporting steadier blood sugar, lower insulin levels, and gradual weight loss.
*Billed quarterly with a three-month commitment paid up front.
WHY BRENZAVVY®
Your kidneys reabsorb glucose. Brenzavvy® can reduce that reabsorption.
Qualitative study evidence
Can block glucose reabsorption
Brenzavvy blocks SGLT2, a protein that pulls sugar back into the bloodstream. Excess glucose exits through urine instead.
Source: FDA-Approved Prescribing Information for Bexagliflozin (Brenzavvy), 2025
Helps lower HbA1c
In a 24-week trial of 207 adults with type 2 diabetes, Brenzavvy lowered HbA1c by 0.4% more than placebo.
Source: FDA-Approved Prescribing Information for Bexagliflozin (Brenzavvy), Clinical Trials 1 & 2, 2025
Has been shown to aid weight loss
A review of eight clinical trials found Brenzavvy lowered blood sugar, reduced body weight by 1.8 kg, and dropped systolic blood pressure by 4 mmHg compared to placebo.
Source: Dholariya et al., Expert Opinion on Pharmacotherapy (2023) — Systematic Review & Meta-Analysis of Bexagliflozin Trials
Charts and graphics are illustrative representations intended to communicate published research findings and the known pharmacologic properties of the referenced medication. Visualizations may simplify, normalize, or model study data for educational purposes and should not be interpreted as guarantees of individual clinical outcomes or expected results.
HOW BRENZAVVY® WORKS
Kidney support.
Glucose control. Brenzavvy® works on one mechanism in your kidneys with two potential benefits: less glucose reabsorption and steadier blood sugar.
Blocks SGLT2
SGLT2 is a kidney protein that recycles roughly 90% of filtered glucose back into your blood. Brenzavvy® can block it, cutting reabsorption by 30–60%.
Metabolic shift
The glucose your body flushes out carries calories with it. Over time, this can support gradual weight loss and may reduce strain on the heart and kidneys.
Glucose excreted
Once blocked, glucose leaves through your urine instead of being recycled. This can help lower blood sugar levels without requiring insulin.
Step 1
Medical intake
Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.
A few minutes
Step 2
Doctor review
A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*
Within 72 hours
Step 3
Fast shipping
Approved medications ship directly to your door in discreet packaging.
2-5 business days
Step 4
Unlimited messaging
Your doctor is available via chat any time for additional support. Video consults available. The same prescription framework as REG3N's medical team. *Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.
Up to 12 months
Proactive care
Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.
Transparent pricing
No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.
Board-certified doctors
Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.
Curated by longevity experts
Every protocol is built by medical experts, based on longevity research from REG3N's science team.
What is Brenzavvy®?
Brenzavvy® (bexagliflozin) is an FDA-approved treatment for type 2 diabetes. Off-label, the broader SGLT2 inhibitor class has been associated with reduced cardiovascular and all-cause mortality in large studies of patients with diabetes and heart failure. How to take Brenzavvy® Brenzavvy® is an oral tablet. Take it once daily, when you wake up, with or without food. Always follow your doctor's instructions.
What are the common side effects associated with Brenzavvy®?
Common side effects include vaginal yeast infections, urinary tract infection, and increased urination. Increased hydration is important while your body adjusts to treatment. Contact your doctor if side effects are persistent or bothersome.
Who shouldn't take Brenzavvy®?
Brenzavvy® is not recommended for people with severe kidney impairment, a history of lower limb amputations, or diabetic foot ulcers. Your doctor will evaluate whether Brenzavvy is appropriate for you.!
Disclaimer: This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program.
Can help kidneys flush excess glucose, supporting steadier blood sugar, lower insulin levels, and gradual weight loss.