Foundayo® (Tablets)
- Product overview
- Why Foundayo®
- How it works
- Treatment process
- Explore other treatments
- Why REG3N
- Common questions
- Treatment information
(orforglipron)
From $750/mo*
Activates GLP-1 receptors, the gut hormone that signals appetite and satiety, supporting weight reduction and long-term weight maintenance.
*Billed quarterly with a three-month commitment paid up front.
WHY FOUNDAYO®
Your hormones tell you when you're full. Foundayo® can mimic that hormone.
Can reduce body weight
In a trial of over 3,100 adults with obesity, Foundayo® produced an average 11.2% body weight reduction over 72 weeks.
Source: Wharton et al., "Daily Oral GLP-1 Receptor Agonist Orforglipron for Adults With Obesity," New England Journal of Medicine (2023) — Phase 2 Trial & Rubin, "Data on 3 New GLP-1 Drugs for Weight Loss," JAMA (2026)
Published study facts
Supports heart and metabolic health
Foundayo® also improved waist circumference, blood pressure, triglycerides, and non-HDL cholesterol.
Source: Wharton et al., "Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity Treatment," New England Journal of Medicine (2025) — ATTAIN-1 Trial
May support lasting results
An earlier phase 2 trial of 272 adults showed up to 14.7% weight loss at 36 weeks, with weight still declining at study end.
Source: Wharton et al., "Daily Oral GLP-1 Receptor Agonist Orforglipron for Adults With Obesity," New England Journal of Medicine (2023) — Phase 2 Trial & Rubin, "Data on 3 New GLP-1 Drugs for Weight Loss," JAMA (2026)
Charts and graphics are illustrative representations intended to communicate published research findings and the known pharmacologic properties of the referenced medication. Visualizations may simplify, normalize, or model study data for educational purposes and should not be interpreted as guarantees of individual clinical outcomes or expected results.
HOW FOUNDAYO® WORKS
Slows digestion.
Aids weight loss. Foundayo® activates GLP-1 receptors, the same target as injectable GLP-1s, supporting appetite control, weight loss, and metabolic health.
Activates GLP-1 receptors
Foundayo® activates GLP-1 receptors in brain regions that regulate appetite and caloric intake.
Supports weight loss
In clinical trials, daily oral dosing produced up to 11.1% mean weight loss at 72 weeks in adults with a high BMI.
Helps reduce appetite
With reduced appetite, people taking Foundayo® typically consume fewer calories. Foundayo® can delay gastric emptying, extending the feeling of fullness after each meal.
Step 1
Medical intake
Answer a guided set of questions covering your medical history, current medications, goals, and treatment preferences.
A few minutes
Step 2
Doctor review
A U.S.-licensed, board-certified physician reviews your intake and recommends a medication, if appropriate.*
Within 72 hours
Step 3
Fast shipping
Approved medications ship directly to your door in discreet packaging.
2-5 business days
Step 4
Unlimited messaging
Your doctor is available via chat any time for additional support. Video consults available. The same prescription framework as REG3N's medical team. *Some states may require a synchronous audio and/or video consultation prior to a prescription being approved.
Up to 12 months
Proactive care
Doctor-led treatment plans designed around your goals. No wait lists. No insurance required.
Transparent pricing
No membership fees, no hidden costs. You pay only after a doctor prescribes treatment.
Board-certified doctors
Access to specialist physicians, licensed in your state. Unlimited messaging for up to 12 months.
Curated by longevity experts
Every protocol is built by medical experts, based on longevity research from REG3N's science team.
What is Foundayo®?
Foundayo® (orforglipron) is a once-daily GLP-1 oral tablet that is FDA-approved for chronic weight management in adults with a high BMI and at least one weight-related comorbid condition. It is sometimes prescribed off-label by doctors within a longevity framework.
How do you take Foundayo®?
Foundayo® is a daily oral tablet, taken with or without food at any time of day. Tablets must be swallowed whole, not broken, crushed, or chewed. Always follow the dosage instructions from your doctor.
What are the side effects of Foundayo®?
The most frequently reported side effects are nausea, constipation, diarrhea, vomiting, and abdominal pain, particularly during dose escalation. Headache, fatigue, and hair loss have also been reported. These are typically mild to moderate and tend to resolve as your body adjusts. Tell your doctor if side effects persist or feel disruptive.
Who shouldn't take Foundayo®?
Foundayo® is contraindicated in people with a personal or family history of medullary thyroid carcinoma or MEN 2 due to the boxed warning for thyroid C-cell tumor risk. It is also not recommended during pregnancy, in people with severe gastroparesis, or in those with severe hepatic impairment. Your doctor will review your full medication list and health history before prescribing.
Disclaimer: This page is intended for educational purposes only and is not intended to provide medical advice, diagnosis or treatment. Medication eligibility and prescriptions are determined solely by licensed medical providers based on clinical appropriateness. Not all individuals will qualify for medication-based treatment. Always consult a licensed healthcare professional before beginning any wellness program.
Activates GLP-1 receptors, the gut hormone that signals appetite and satiety, supporting weight reduction and long-term weight maintenance.